{"product_id":"selank","title":"Selank","description":"\u003ch2\u003eSelank 10mg Research Peptide\u003c\/h2\u003e\n\u003cp\u003eSelank 10mg is a lyophilized peptide for laboratory research. Pricing and availability are shown above.\u003c\/p\u003e\n\u003ch3\u003eCOAs and product documentation\u003c\/h3\u003e\n\u003cp\u003eFind available reports in our \u003ca href=\"\/pages\/coa\"\u003eCOA library\u003c\/a\u003e. Match the product name and lot number to the material you plan to order. For a specific report or test requirement, contact \u003ca href=\"\/pages\/contact\"\u003eOptimum Peptide support\u003c\/a\u003e before purchase.\u003c\/p\u003e\n\u003cp\u003eFor larger quantities or regular orders, \u003ca href=\"\/pages\/wholesale\"\u003esend a wholesale inquiry\u003c\/a\u003e with the product name and quantity required.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/selank-research-guide\"\u003eRead the Selank research guide\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or veterinary use, diagnosis, treatment, or clinical application.\u003c\/p\u003e\n\u003csection class=\"product-research-information\"\u003e\u003ch2\u003eProduct research information\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Name:\u003c\/strong\u003e Selank (TP-7)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 129954-34-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₃₃H₅₇N₁₁O₉\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 751.9 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Thr-Lys-Pro-Arg-Pro-Gly-Pro\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnalytical results:\u003c\/strong\u003e Review documentation for the exact supplied lot.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized White Powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in bacteriostatic water or sterile water\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSelank is a synthetic peptide with the molecular formula \u003cstrong\u003eC₃₃H₅₇N₁₁O₉\u003c\/strong\u003e. It is structurally composed of the tetrapeptide Tuftsin (Thr-Lys-Pro-Arg) with the addition of a Pro-Gly-Pro sequence at the C-terminus. This structural modification is hypothesized to improve the metabolic stability of the peptide in biological mediums compared to endogenous ligands.\u003c\/p\u003e\n\u003cp\u003eScientific investigations have focused on Selank’s ability to modulate the expression of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus of murine models. Furthermore, studies suggest that the peptide may inhibit the enzymatic degradation of enkephalins, which are endogenous peptides involved in nociception and stress response. This inhibition is believed to extend the half-life of these regulatory molecules within the nervous system.\u003c\/p\u003e\n\u003cp\u003eIn behavioral research utilizing rat models, Selank has been observed to affect dopamine and serotonin turnover rates in the frontal cortex. Researchers explore these pathways to understand potential mechanisms related to anxiety-like behavior, memory retention, and learning processes. The peptide is also subject to studies regarding its immunomodulatory properties due to its Tuftsin lineage.\u003c\/p\u003e\n\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eSemenova, T. P., et al. (2010). “Comparison of the effects of selank and tuftsin on the metabolism of serotonin, dopamine, and norepinephrine in the brain of mice with different phenotypes of emotional and behavioral reactions.” \u003cem\u003eNeuroscience and Behavioral Physiology\u003c\/em\u003e, 40(9), 1007-1012.\u003c\/li\u003e\n\u003cli\u003eKozlovskaya, M. M., et al. (2003). “Selank and short peptides of the tuftsin family in the regulation of adaptive behavior in stress.” \u003cem\u003eNeuroscience and Behavioral Physiology\u003c\/em\u003e, 33(9), 853-860.\u003c\/li\u003e\n\u003cli\u003eUshakova, V. M., et al. (2017). “Gene expression in the hippocampus of rats with different variants of behavior in the elevated plus-maze test under basal conditions and after administration of the peptide selank.” \u003cem\u003eRussian Journal of Genetics\u003c\/em\u003e, 53(2), 239-246.\u003c\/li\u003e\n  \u003c\/ol\u003e\u003c\/section\u003e","brand":"Optimum Peptide","offers":[{"title":"10 MG","offer_id":67872530628974,"sku":"SELANK10MG","price":55.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1023\/8571\/3518\/files\/optimum-selank.png?v=1792938736","url":"https:\/\/optimumpeptide.com\/products\/selank","provider":"Optimum Peptide","version":"1.0","type":"link"}